Disruption of HAUSP gene stabilizes p53
Top Cited Papers
- 1 April 2004
- journal article
- editorial
- Published by Springer Science and Business Media LLC in Nature
- Vol. 428 (6982), 1-2
- https://doi.org/10.1038/nature02501
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated virusesNucleic Acids Research, 2004
- The p53–Mdm2 module and the ubiquitin systemSeminars in Cancer Biology, 2002
- Crystal Structure of a UBP-Family Deubiquitinating Enzyme in Isolation and in Complex with Ubiquitin AldehydeCell, 2002
- Deconstruction of p53 functions and regulationOncogene, 2002
- Targeted transgene insertion into human chromosomes by adeno-associated virus vectorsNature Biotechnology, 2002
- Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilizationNature, 2002
- Disruption of p53 in human cancer cells alters the responses to therapeutic agentsJCI Insight, 1999
- A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory proteinThe EMBO Journal, 1997
- Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53Nature, 1995
- Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53Nature, 1995