The discovery of potent cRaf1 kinase inhibitors
- 22 February 2000
- journal article
- research article
- Published by Elsevier BV in Bioorganic & Medicinal Chemistry Letters
- Vol. 10 (3), 223-226
- https://doi.org/10.1016/s0960-894x(99)00668-x
Abstract
No abstract availableKeywords
This publication has 10 references indexed in Scilit:
- A Scintillation Proximity Assay for the Raf/MEK/ERK Kinase Cascade: High-Throughput Screening and Identification of Selective Enzyme InhibitorsAnalytical Biochemistry, 1999
- Synthesis and Biological Evaluations of 3-Substituted Indolin-2-ones: A Novel Class of Tyrosine Kinase Inhibitors That Exhibit Selectivity toward Particular Receptor Tyrosine KinasesJournal of Medicinal Chemistry, 1998
- Structures of the Tyrosine Kinase Domain of Fibroblast Growth Factor Receptor in Complex with InhibitorsScience, 1997
- Apoptosis Meets Signal Transduction: Elimination of a BAD InfluenceCell, 1996
- Bcl-2 Targets the Protein Kinase Raf-1 to MitochondriaCell, 1996
- Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1.Proceedings of the National Academy of Sciences of the United States of America, 1996
- Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinaseNature Medicine, 1996
- Raf-1 protein kinase is required for growth of induced NIH/3T3 cellsNature, 1991
- Specific inhibitors of tyrosine-specific protein kinase, synthetic 4-hydroxycinnamamide derivativesBiochemical and Biophysical Research Communications, 1987
- Serine- and threonine-specific protein kinase activities of purified gag–mil and gag–raf proteinsNature, 1984