Meta‐analysis of laparoscopy‐assisted distal gastrectomy with D2 lymph node dissection for gastric cancer
- 22 September 2011
- journal article
- research article
- Published by Wiley in Journal of Surgical Oncology
- Vol. 105 (3), 297-303
- https://doi.org/10.1002/jso.22098
Abstract
Background To assess the value of laparoscopy‐assisted distal gastrectomy with D2 dissection for treatment of gastric cancer. Methods We collected studies that have compared laparoscopy‐assisted distal gastrectomy (LADG) and open distal gastrectomy (ODG) with D2 dissection for treatment of gastric cancer in the past 15 years. Data of interest for LADG and ODG were subjected to meta‐analysis using a fixed‐effect and random‐effect model. Results We analyzed 8 studies that included 1,065 patients. There were significant differences in operating time, blood loss, time to first flatus and first eating, postoperative hospital stay, and postoperative complications between the LADG and ODG groups. Compared with the ODG group, blood loss and complications in the LADG group decreased, time to recovery of gastrointestinal function and hospitalization period were shorter, but operating time was longer. There were no significant differences in the number of harvested lymph nodes, mortality, and rate of recurrence between the groups. Conclusions Compared with ODG, LADG with D2 dissection has the advantages of minimal invasion, faster recovery, and fewer complications, and it can achieve the same degree of radicality and short‐term prognosis as ODG. The drawbacks are that the operating time is slightly longer and long‐term prognosis is not clear. J. Surg. Oncol. 2012; 105:297–303.Keywords
This publication has 23 references indexed in Scilit:
- Comparison of long-term outcomes of laparoscopy-assisted and open distal gastrectomy for early gastric cancerSurgical Endoscopy, 2008
- Laparoscopy‐assisted distal gastrectomy with D2 lymphadenectomy for T2b advanced gastric cancers: Three Years' experienceJournal of Surgical Oncology, 2008
- Totally Laparoscopic Radical BII Gastrectomy for the Treatment of Gastric CancerSurgical Laparoscopy, Endoscopy & Percutaneous Techniques, 2008
- Inspection of Safety and Accuracy of D2 Lymph Node Dissection in Laparoscopy‐Assisted Distal GastrectomyWorld Journal of Surgery, 2008
- Laparoscopy-assisted distal gastrectomy with D2 lymph node dissection for gastric cancer: technical and oncologic aspectsSurgical Endoscopy, 2007
- Management of Gastroesophageal TumorsThe Oncologist, 2007
- Laparoscopically assisted distal gastrectomy with standard radical lymph node dissection for gastric cancerSurgical Endoscopy, 2005
- Off-pump myocardial revascularization is associated with less incidence of stroke in elderly patientsThe Annals of Thoracic Surgery, 2004
- Japanese Classification of Gastric Carcinoma – 2nd English Edition –Gastric Cancer, 1998
- Early international results of laparoscopic gastrectomies.Surgical Endoscopy, 1997