The dinB Operon and Spontaneous Mutation in Escherichia coli
- 1 July 2003
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 185 (13), 3972-7
- https://doi.org/10.1128/jb.185.13.3972-3977.2003
Abstract
Apparently conflicting data regarding the role of SOS-inducible, error-prone DNA polymerase IV (DinB) in spontaneous mutation are resolved by the finding that mutation is reduced by a polar allele with which dinB and neighboring yafN are deleted but not by two nonpolar dinB alleles. We demonstrate the existence of a dinB operon that contains four genes, dinB - yafN - yafO - yafP . The results imply a role for yafN , yafO , and/or yafP in spontaneous mutation.Keywords
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