The Constitutive Androstane Receptor Is an Anti-obesity Nuclear Receptor That Improves Insulin Sensitivity
Open Access
- 1 September 2009
- journal article
- Published by Elsevier BV in Journal of Biological Chemistry
- Vol. 284 (38), 25984-25992
- https://doi.org/10.1074/jbc.m109.016808
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- Constitutive androstane receptor mediates the induction of drug metabolism in mouse models of type 1 diabetesHepatology, 2009
- UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master RegulatorsDevelopmental Cell, 2008
- Androgen Deprivation by Activating the Liver X ReceptorEndocrinology, 2008
- PPARα‐dependent induction of the energy homeostasis‐regulating nuclear receptor NR1i3 (CAR) in rat hepatocytes: Potential role in starvation adaptationFEBS Letters, 2007
- Human nuclear pregnane X receptor cross-talk with CREB to repress cAMP activation of the glucose-6-phosphatase geneBiochemical Journal, 2007
- Mechanisms linking obesity to insulin resistance and type 2 diabetesNature, 2006
- Regulation of Constitutive Androstane Receptor and Its Target Genes by Fasting, cAMP, Hepatocyte Nuclear Factor α, and the Coactivator Peroxisome Proliferator-activated Receptor γ Coactivator-1αPublished by Elsevier BV ,2006
- PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3Nature Medicine, 2004
- Dexamethasone induction of hypertension and diabetes is PPAR-α dependent in LDL receptor–null miceNature Medicine, 2003
- Neuropeptide Y (NPY) May Integrate Responses of Hypothalamic Feeding Systems and the Hypothalamo‐Pituitary‐Adrenal AxisJournal of Neuroendocrinology, 1995