Restoration of the Meniscus
- 12 August 2013
- journal article
- review article
- Published by SAGE Publications in The American Journal of Sports Medicine
- Vol. 42 (4), 987-998
- https://doi.org/10.1177/0363546513498503
Abstract
Over the past 2 decades there has been a profound shift in our perception of the role of the meniscus in the knee joint. Orthopaedic opinion now favors salvaging and restoring the damaged meniscus where possible. Basic science is characterizing its form (anatomy) and functionality (biological and biomechanical) in an attempt to understand the effect of meniscal injury and repair on the knee joint as a whole. The meniscus is a complex tissue and has warranted extensive basic science, translational, and clinical research to identify techniques to augment healing and even replace the meniscus. The application of quantitative magnetic resonance image sequencing to the meniscus and articular cartilage of the affected compartment promises to add a quantifiable outcome measure to the body of clinical evidence that supports restoration of the meniscus. This article discusses the recent advances and outcomes in the pursuit of meniscal restoration with particular focus on the use of augmentation strategies in meniscal repair, meniscal imaging, and translational strategies.This publication has 98 references indexed in Scilit:
- Augmentation techniques for isolated meniscal tearsCurrent Reviews in Musculoskeletal Medicine, 2013
- Osteoarthritis: A disease of the joint as an organArthritis & Rheumatism, 2012
- Fiber angle and aspect ratio influence the shear mechanics of oriented electrospun nanofibrous scaffoldsJournal of the Mechanical Behavior of Biomedical Materials, 2011
- The knee meniscus: Structure–function, pathophysiology, current repair techniques, and prospects for regenerationBiomaterials, 2011
- Design and mechanical evaluation of a novel fiber‐reinforced scaffold for meniscus replacementJournal of Biomedical Materials Research Part A, 2011
- Frictional Properties of the Meniscus Improve After Scaffold-augmented Repair of Partial Meniscectomy: A Pilot StudyClinical Orthopaedics and Related Research, 2011
- Cell-based Meniscal Tissue Engineering: A Case for SynoviocytesClinical Orthopaedics and Related Research, 2011
- The MSC: An Injury DrugstoreCell Stem Cell, 2011
- Multifunctional Hybrid Three‐dimensionally Woven Scaffolds for Cartilage Tissue EngineeringMacromolecular Bioscience, 2010
- Effects of TGF-β1 and hydrostatic pressure on meniscus cell-seeded scaffoldsBiomaterials, 2009