Arginine extravasation leading to skin necrosis
- 29 April 2011
- journal article
- case report
- Published by Wiley in Journal of Paediatrics and Child Health
- Vol. 48 (3), E96-E97
- https://doi.org/10.1111/j.1440-1754.2011.02074.x
Abstract
Arginine hydrochloride is used in the evaluation of short stature and in the management of urea cycle disorders. In recent times, it has been used in the treatment of stroke-like episodes of MELAS (mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes). We want to highlight the need for good intravenous access and monitoring the drip site to prevent extravasation injuries that can be caused by arginine, which is a hyperosmolar solution.Keywords
This publication has 9 references indexed in Scilit:
- Cutaneous Necrosis Induced by Extravasation of Arginine MonohydrochlorideActa Dermato-Venereologica, 2008
- Case of skin necrosis due to arginine monohydrochloride extravasationThe Journal of Dermatology, 2007
- Endothelial dysfunction in MELAS improved by l-arginine supplementationNeurology, 2006
- Case 36-2005: A Woman with Seizure, Disturbed Gait, and Altered Mental StatusNew England Journal of Medicine, 2006
- l -Arginine improves the symptoms of strokelike episodes in MELASNeurology, 2005
- Full-thickness skin necrosis after arginine extravasation—a case report and review of literatureJournal of Pediatric Surgery, 2004
- Effects of l -arginine on the acute phase of strokes in three patients with MELASNeurology, 2002
- Extravasation injuriesBritish Journal of Plastic Surgery, 1993
- Management of Arginine Monohydrochloride Extravasation in the ForearmSouthern Medical Journal, 1991