Synthesis and Biological Evaluation of Macrocyclized Betulin Derivatives as a Novel Class of Anti-HIV-1 Maturation Inhibitors
Open Access
- 3 September 2014
- journal article
- Published by Bentham Science Publishers Ltd. in The Open Medicinal Chemistry Journal
- Vol. 8 (1), 23-27
- https://doi.org/10.2174/1874104501408010023
Abstract
Synthesis and Biological Evaluation of Macrocyclized Betulin Derivatives as a Novel Class of Anti-HIV-1 Maturation InhibitorsKeywords
This publication has 12 references indexed in Scilit:
- Synthesis and biological evaluation of a new derivative of bevirimat that targets the Gag CA-SP1 cleavage siteEuropean Journal of Medicinal Chemistry, 2013
- New Betulinic Acid Derivatives for Bevirimat-Resistant Human Immunodeficiency Virus Type-1Journal of Medicinal Chemistry, 2013
- Anti-AIDS Agents 90. Novel C-28 Modified Bevirimat Analogues as Potent HIV Maturation InhibitorsJournal of Medicinal Chemistry, 2012
- Prevalence and Clinical Significance of HIV Drug Resistance Mutations by Ultra-Deep Sequencing in Antiretroviral-Naïve Subjects in the CASTLE StudyPLOS ONE, 2010
- Transmission of HIV‐1 Drug‐Resistant Variants: Prevalence and Effect on Treatment OutcomeClinical Infectious Diseases, 2010
- Novel approaches to inhibiting HIV-1 replicationAntiviral Research, 2010
- HIV entry inhibitors and their potential in HIV therapyMedicinal Research Reviews, 2008
- Betulinic acid derivatives as HIV-1 antiviralsTrends in Molecular Medicine, 2005
- Small-Molecule Inhibition of Human Immunodeficiency Virus Type 1 Replication by Specific Targeting of the Final Step of Virion MaturationJournal of Virology, 2004
- PA-457: A potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processingProceedings of the National Academy of Sciences of the United States of America, 2003