The association of embryonal tumors originating in the kidney and in the brain. A report of seven cases
- 15 November 1984
- Vol. 54 (10), 2137-2146
- https://doi.org/10.1002/1097-0142(19841115)54:10<2137::aid-cncr2820541014>3.0.co;2-d
Abstract
This report documents, in seven infants younger than 2 years of age, a previously unrecognized association of a renal embryonal neoplasm (malignant rhabdoid tumor in six patients and a Wilms' tumor in one) with an embryonal primary tumor originating in the central nervous system. The neuroepithelial tumors included three cerebellar medulloblastomas, one pineoblastoma, one primitive neuroepithelial tumor (probably cerebral neuroblastoma), one malignant subependymal giant cell astrocytoma, and one cerebellar medulloepithelioma with divergent glial and neuronal differentiation. There is no evidence that this association is based on the selective neoplastic transformation of embryonal cells of similar histogenetic or cytogenetic origin. The relationship between these dissimilar, embryologically unrelated tumors remains enigmatic.Keywords
This publication has 28 references indexed in Scilit:
- Intraventricular neuroblastoma in a patient with Von Hippel-Lindau's diseaseActa Neuropathologica, 1981
- Rhabdoid tumor of the kidney: Complete remission induced by cis-platinum and adriamycinMedical and Pediatric Oncology, 1981
- Presence of ganglion cells in Wilm's tumours: a review of the possible neuroepithelial origin of nephroblastomaHistopathology, 1980
- Colon polyps, sebaceous cysts, gastric polyps, and malignant brain tumor in a familyDigestive Diseases and Sciences, 1978
- Dilemma in a case of Turcot's (glioma-polyposis) syndromeDiseases of the Colon & Rectum, 1975
- Neurological involvement in the nevoid basal cell carcinoma syndromeJournal of Neurosurgery, 1971
- Medulloblastoma in Newborn SistersJournal of Neurosurgery, 1969
- Malignant tumors of the central nervous system associated with familial polyposis of the colonDiseases of the Colon & Rectum, 1959
- A congenital medulloepithelioma of the midbrainThe Journal of Pathology and Bacteriology, 1957
- The Role of the Neural Crests in the Embryonal Adenosarcomas of the KidneyThe American Journal of Cancer, 1938