Three new metabolites have been isolated from cultures of Streptomyces caeruleus and are related to caerulomycin, a known antibiotic metabolite of this organism now designated caerulomycin A. The structures of two of the new compounds, caerulomycins B and C, are shown to be 3-hydroxy-4-methoxy- and 3,4-dimethoxy-2,2′-dipyridyl-6-(E)-aldoxime.