Relaxin's induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint fibrocartilaginous explants
Open Access
- 1 January 2005
- journal article
- research article
- Published by Springer Science and Business Media LLC in Arthritis Research & Therapy
- Vol. 7 (1), R1-11
- https://doi.org/10.1186/ar1451
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Relaxin Increases Secretion of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 during Uterine and Cervical Growth and Remodeling in the PigEndocrinology, 2001
- Relaxin Positively Regulates Matrix Metalloproteinase Expression in Human Lower Uterine Segment Fibroblasts Using a Tyrosine Kinase Signaling PathwayEndocrinology, 2001
- Relaxin: A pleiotropic hormoneGeneral Pharmacology: The Vascular System, 1997
- Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent.JCI Insight, 1996
- The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. A role in osteoarthritis.JCI Insight, 1996
- The effects of oestradiol and relaxin on extensibility and collagen organisation of the pregnant rat cervixJournal of Endocrinology, 1995
- Characterization and Identification of Proteinases and Proteinase Inhibitors Synthesized by Temporomandibular Joint Disc CellsJournal of Dental Research, 1995
- Cellular shape and pressure may mediate mechanical control of tissue composition in tendonsJournal of Orthopaedic Research, 1993
- Effect of relaxin on the phenotype of collagens synthesized by cultured rabbit chondrocytesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1988
- Relaxin and Collagen MetabolismHormone and Metabolic Research, 1979