Partial ADAMTS13 deficiency in atypical hemolytic uremic syndrome
Open Access
- 22 August 2013
- journal article
- Published by American Society of Hematology in Blood
- Vol. 122 (8), 1487-1493
- https://doi.org/10.1182/blood-2013-03-492421
Abstract
Key Points Reduction in ADAMTS13 function and complement dysregulation coexist in a significant number of patients with aHUS. Variations in the ADAMTS13 gene (polymorphisms and rare variants) are partly responsible for the reduced ADAMTS13 function in aHUS.Keywords
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