Cowden's Disease with Vocal Fold Involvement
Open Access
- 1 October 2001
- journal article
- case report
- Published by SAGE Publications in Ear, Nose & Throat Journal
- Vol. 80 (10), 754-758
- https://doi.org/10.1177/014556130108001015
Abstract
Cowden's disease is a hereditary disorder characterized by oropharyngeal fibrosis and multiple hamartomas with potential malignant changes. We treated a 47-year-old man who had fibrotic lesions on the left vocal fold and an extensive amount of papillomatous lesions on the mucosa of the lips, tongue, and pharyngeal wall and on the skin of the axillae and buttocks. The pattern of distribution and the histopathologic features of these mucocutaneous lesions were diagnostic of Cowden's disease. To the best of our knowledge, this is the first reported case of Cowden's disease involving a vocal fold.Keywords
This publication has 9 references indexed in Scilit:
- Cowden's Syndrome, Lhermitte-Duclos Disease, and Sclerotic FibromaThe American Journal of Dermatopathology, 1998
- Cowden syndrome and lhermitte-duclos diseaseCancer, 1992
- Idiopathic fibrosis of the upper aero-digestive tract.The Journal of Laryngology & Otology, 1989
- The Cowden syndrome: a clinical and genetic study in 21 patientsClinical Genetics, 1986
- Laryngeal AmyloidosisAnnals of Otology, Rhinology & Laryngology, 1977
- Laryngeal involvement in von recklinghausen's disease: A case report and review of the literatureThe Laryngoscope, 1977
- Multiple Hamartoma Syndrome (Cowden's Disease)Archives of Dermatology, 1972
- Familial Multifocal FibrosclerosisAnnals of Internal Medicine, 1967
- Cowden's DiseaseAnnals of Internal Medicine, 1963