Oxygen‐Rich Enzyme Biosensor Based on Superhydrophobic Electrode

Abstract

The fabrication of novel superhydrophobic electrodes is described, which have an air–liquid–solid three-phase interface, where oxygen is sufficient and constant. Oxygen is an effective natural electron acceptor for oxidase, and plays a key role in the development of reliable bioassays. Such an electrode allows detection of glucose concentration, linearly from 50 × 10⁻⁹ m to 156 × 10⁻³ m with good sensitivity and accuracy without analyte dilution. This strategy offers a unique route to address the gas-deficit problem of many reaction systems.