EnhancerAtlas: a resource for enhancer annotation and analysis in 105 human cell/tissue types
Open Access
- 10 August 2016
- journal article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 32 (23), 3543-3551
- https://doi.org/10.1093/bioinformatics/btw495
Abstract
Motivation: Multiple high-throughput approaches have recently been developed and allowed the discovery of enhancers on a genome scale in a single experiment. However, the datasets generated from these approaches are not fully utilized by the research community due to technical challenges such as lack of consensus enhancer annotation and integrative analytic tools.Keywords
Funding Information
- National Institutes of Health (EY024580, GM111514, EY023188, HG006130, GM104369, GM108716)
This publication has 25 references indexed in Scilit:
- An integrated encyclopedia of DNA elements in the human genomeNature, 2012
- The accessible chromatin landscape of the human genomeNature, 2012
- Transcription factors: from enhancer binding to developmental controlNature Reviews Genetics, 2012
- The Human Epigenome Browser at Washington UniversityNature Methods, 2011
- Enhancer function: new insights into the regulation of tissue-specific gene expressionNature Reviews Genetics, 2011
- Widespread transcription at neuronal activity-regulated enhancersNature, 2010
- A map of open chromatin in human pancreatic isletsNature Genetics, 2010
- An oestrogen-receptor-α-bound human chromatin interactomeNature, 2009
- Histone modifications at human enhancers reflect global cell-type-specific gene expressionNature, 2009
- ChIP-seq accurately predicts tissue-specific activity of enhancersNature, 2009