Role of saliva in tick/host interactions

Abstract
Although several hosts mount efficient anti-tick immunity, natural tick/host associations are characterized by inefficient or non-existent anti-tick immunity. The absence of efficient anti-tick immunity in natural hosts could result from either host immune incompetence or the ectoparasite's successful evasion of the host's immune response. In this review I discuss data supporting the immune-evasion hypothesis and discuss its consequences to tick/host interactions.