Effectiveness of Live, Attenuated Intranasal Influenza Virus Vaccine in Healthy, Working Adults

Abstract

Influenza type A and B viruses cause illness in 10% to 20% of the population each year.¹ Prominent manifestations of illness include decreased ability to perform daily activities and increased health care resource use. Among working adults, influenza accounts for millions of work-loss days and physician office visits each year.^2,3 Although healthy, working adults are not currently targeted for routine annual vaccination,⁴ immunization with inactivated influenza virus vaccines can be associated with substantial health and economic benefits for this group.⁵