Prevention and control of mycotoxins in the poultry production chain: a European view
- 1 December 2002
- journal article
- Published by Taylor & Francis Ltd in World's Poultry Science Journal
- Vol. 58 (4), 451-474
- https://doi.org/10.1079/wps20020033
Abstract
Prevention and control of mycotoxins in the poultry production chain requires the knowledge and consideration of all factors influencing mycotoxin formation in the field and during the storage of feedstuffs. Mycotoxin effects on health and performance of poultry and the ‘carry over’ of mycotoxins or their metabolites into foodstuffs of animal origin are also essential information elements. Among a number of known my cotoxins, the Fusarium-mycotoxins deoxynivalenol (DON) and zearalenone (ZON) are of special importance under European production conditions because of their high frequency and concentrations. Several plant production strategies might help to minimize the risk of formation of these mycotoxins. However, higher mean values are unavoidable under unfavourable weather conditions. Therefore, special care must be taken in so-called ‘Fusurium-years’, because poultry is regarded as less sensitive to these mycotoxins than pigs and suspect cereal batches will be diverted to poultry feeding. Higher dietary DON-concentrations adversely affect the performance and immune response of poultry at dietary concentrations of greater than 5 mg per kg diet. In contrast, zearalenone, which often co-occurs with DON, does not cause deleterious effects in poultry even in ‘Fusurium-years’ when higher concentrations are measured. ‘Carry over’ of both toxins into poultry products is very low and is negligible when the DON-concentration of the diet is restricted to this 5 mg per kg. The levels of further Fusurium mycotoxins such as T-2 toxin, fumonisins, moniliformin or beauvericin to be expected in Europe are too low to cause toxic effects in poultry. However, several combinations of co-occurring mycotoxins might influence the total toxic potential of a contaminated feedstuff. Several feed-processing procedures are suitable for reducing the DON-content of contaminated feedstuffs, but they are expensive or have been only lab-tested. Adsorbing agents were shown to either only weakly bind DON, or not to bind it at all in vitro, and to be ineffective in vivo. More recent efforts have been directed at employing the capability of several micro-organisms (bacteria and yeasts) to degrade DON for detoxification in situ.Keywords
This publication has 89 references indexed in Scilit:
- Natural occurrence ofFusaviumtoxins in oats harvested during five years in an area of southwest GermanyFood Additives & Contaminants, 1998
- Effects of polyvinylpolypyrrolidone,synthetic zeolite and bentonite on serum biochemical and haematological characters of broiler chickens during aflatoxicosisBritish Poultry Science, 1998
- The preventive effect of polyvinylpolypyrrolidone on aflatoxicosis in broilersAvian Pathology, 1998
- Untersuchung und Bewertung der Fumonisinkontamination von einheimischem und importiertem GetreideZeitschrift für Lebensmittel-Untersuchung und Forschung, 1996
- Invited Review: TOXICOLOGY OF DEOXYNIVALENOL (VOMITOXIN)Journal of Toxicology and Environmental Health, 1996
- Mycotoxicosis: mechanisms of immunosuppressionVeterinary Immunology and Immunopathology, 1991
- A survey of the occurrence of the mycotoxin moniliformin in cereal samples from sources worldwideFood Additives & Contaminants, 1991
- Hematologic and immunologic toxicity of deoxynivalenol (DON)-contaminated diets to growing chickensBulletin of Environmental Contamination and Toxicology, 1991
- A practical guide to the prevention ofFusarium mycotoxins in grain and animal feedstuffsArchives of Environmental Contamination and Toxicology, 1989
- Evidence for in vitro and in vivo interaction between ochratoxin A and three acidic drugsFood and Cosmetics Toxicology, 1980