Effect of Different Aldehydes on Tracheal Mucosa
- 1 May 1971
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery
- Vol. 93 (5), 496-500
- https://doi.org/10.1001/archotol.1971.00770060742011
Abstract
In connection with investigations of the ciliostatic effect of tobacco smoke, aldehydes have been of special interest as many of them have an irritating effect on the tracheal mucosa. A comparison of the ciliostatic effect of formaldehyde, acrolein, acetaldehyde, crotonaldehyde, and methacrolein shows that there are significant differences between the substance's regression lines. Formaldehyde seems to be the most toxic substance followed by acetaldehyde and acrolein. Crotonaldehyde and methacrolein have the weakest slope. The technique for observing the tracheal ciliary activity is the in vitro technique which has been used in many other investigations.Keywords
This publication has 6 references indexed in Scilit:
- Ciliotoxicity of cigarette smoke and its volatile components.Published by Elsevier BV ,1968
- Ciliostatic Effect of Phenol and ResorcinolJAMA Otolaryngology–Head & Neck Surgery, 1966
- Components of Cigarette Smoke with Ciliary-Depressant ActivityNew England Journal of Medicine, 1963
- Spectrophotometric Determination of Crotonaldehyde with 4-HexylresorcinolAnalytical Chemistry, 1961
- A New Spectrophotometric Method for Determination of Acrolein in Combustion Gases and in the AtmosphereAnalytical Chemistry, 1961
- Microdetermination of Free FormaldehydeAnalytical Chemistry, 1951