Benefits and Harms of Statin Therapy for Persons With Chronic Kidney Disease
- 21 August 2012
- journal article
- research article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 157 (4), 263-75
- https://doi.org/10.7326/0003-4819-157-4-201208210-00007
Abstract
Whether effects of statin therapy in persons with CKD vary with severity of CKD is uncertain. This review of 89 trials summarizes evidence on the benefits and harms of statin therapy for adults wit... Background: Statins have uncertain benefits in persons with chronic kidney disease (CKD) because individual trials may have insufficient power to determine whether treatment effects differ with sev...Keywords
This publication has 99 references indexed in Scilit:
- Rosuvastatin and Cardiovascular Events in Patients Undergoing HemodialysisNew England Journal of Medicine, 2009
- The ABCs of Cardioprotection in Dialysis Patients: A Systematic ReviewAmerican Journal of Kidney Diseases, 2009
- Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive ProteinNew England Journal of Medicine, 2008
- GRADE: an emerging consensus on rating quality of evidence and strength of recommendationsBMJ, 2008
- Effects of statins in patients with chronic kidney disease: meta-analysis and meta-regression of randomised controlled trialsBMJ, 2008
- A modified test for small‐study effects in meta‐analyses of controlled trials with binary endpointsStatistics in Medicine, 2005
- Advanced methods in meta‐analysis: multivariate approach and meta‐regressionStatistics in Medicine, 2002
- Psycho-Social Aspects of Serious Renal Disease and DialysisSocial Work in Health Care, 1998
- Clinical Pharmacokinetics of NefazodoneClinical Pharmacokinetics, 1997
- Meta-analysis in clinical trialsControlled Clinical Trials, 1986