ATR and H2AX Cooperate in Maintaining Genome Stability under Replication Stress
Open Access
- 27 February 2009
- journal article
- Published by Elsevier BV
- Vol. 284 (9), 5994-6003
- https://doi.org/10.1074/jbc.m806739200
Abstract
No abstract availableThis publication has 60 references indexed in Scilit:
- RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein AssemblyCell, 2007
- Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesisThe EMBO Journal, 2007
- Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell LossCell Stem Cell, 2007
- Increased Common Fragile Site Expression, Cell Proliferation Defects, and Apoptosis following Conditional Inactivation of MouseHus1in Primary Cultured CellsMolecular Biology of the Cell, 2007
- Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stabilityThe EMBO Journal, 2007
- A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sitesThe EMBO Journal, 2006
- ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaksThe EMBO Journal, 2006
- Activation of the DNA damage checkpoint and genomic instability in human precancerous lesionsNature, 2005
- DNA damage response as a candidate anti-cancer barrier in early human tumorigenesisNature, 2005
- Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.Genes & Development, 1994