Thrombolysis for stroke caused by infective endocarditis: an illustrative case and review of the literature
- 5 January 2013
- journal article
- case report
- Published by Springer Science and Business Media LLC in Zeitschrift für Neurologie
- Vol. 260 (5), 1339-1342
- https://doi.org/10.1007/s00415-012-6802-1
Abstract
Infective endocarditis represents a classical contra-indication to thrombolysis for acute ischemic stroke due to a potential increased risk of intracranial hemorrhage. However, some case reports have suggested safety and potential efficacy of intravenous or intra-arterial thrombolysis in stroke related to infective endocarditis. We present a case of ischemic stroke related to infective endocarditis who was treated with intravenous tissue plasminogen activator within the first 3 h of symptoms onset and subsequently developed symptomatic multifocal intracerebral hemorrhages, and summarize currently available data on this issue.Keywords
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