Expanded Modes of Tissue Plasminogen Activator Delivery in a Comprehensive Stroke Center Increases Regional Acute Stroke Interventions
- 1 June 2003
- journal article
- Published by Ovid Technologies (Wolters Kluwer Health) in Stroke
- Vol. 34 (6), e58-60
- https://doi.org/10.1161/01.str.0000071107.66925.93
Abstract
Background and Purpose— We sought to evaluate whether a comprehensive stroke center could work with regional hospitals to increase the use of tissue plasminogen activator (tPA) in acute stroke. Methods— In 30 months, 142 patients seen at the Mid America Brain and Stroke Institute received tPA. Site of presentation, protocol selection, and outcomes were analyzed. Results— We found that 18.2% (142 of 781) of all ischemic strokes received tPA. Of those, 70% (99 of 142) were transferred from hospitals within 100 miles of Kansas City (Mo). Mortality rate was 12.7% (18 of 142). Symptomatic hemorrhage rate was 9.2%. Conclusions— A comprehensive stroke center can serve as a hub for a regional network and increase the number of stroke interventions with acceptable outcomes.This publication has 5 references indexed in Scilit:
- Intravenous Tissue-Type Plasminogen Activator Therapy for Ischemic StrokeArchives of Neurology, 2001
- Early stroke treatment associated with better outcomeNeurology, 2000
- Intravenous Tissue-Type Plasminogen Activator for Treatment of Acute StrokeJAMA, 2000
- Intra-arterial Prourokinase for Acute Ischemic StrokeJAMA, 1999
- Tissue Plasminogen Activator for Acute Ischemic StrokeNew England Journal of Medicine, 1995