Chromatin immunoprecipitation from fixed clinical tissues reveals tumor-specific enhancer profiles

25 April 2016

journal article
research article
Published by Springer Science and Business Media LLC in Nature Medicine

Vol. 22 (6), 685-691
https://doi.org/10.1038/nm.4085

Abstract

Fixed-tissue chromatin immunoprecipitation sequencing (FiT-seq) enables accurate detection of histone marks on chromatin extracted from formalin-fixed paraffin-embedded (FFPE) tissue samples.

Keywords

This publication has 37 references indexed in Scilit:

Integrative analysis of 111 reference human epigenomes
Nature, 2015
HTSeq—a Python framework to work with high-throughput sequencing data
Bioinformatics, 2014
Super-Enhancers in the Control of Cell Identity and Disease
Cell, 2013
Lessons from the Cancer Genome
Cell, 2013
Computational methodology for ChIP‐seq analysis
Quantitative Biology, 2013
Increased methylation variation in epigenetic domains across cancer types
Nature Genetics, 2011
Genome-Wide Pattern of TCF7L2/TCF4 Chromatin Occupancy in Colorectal Cancer Cells
Molecular and Cellular Biology, 2008
A core Klf circuitry regulates self-renewal of embryonic stem cells
Nature, 2008
Genome-wide analysis of estrogen receptor binding sites
Nature Genetics, 2006
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
Proceedings of the National Academy of Sciences of the United States of America, 2005

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