Circadian Time of Morning Light Administration and Therapeutic Response in Winter Depression
Open Access
- 1 January 2001
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of General Psychiatry
- Vol. 58 (1), 69-75
- https://doi.org/10.1001/archpsyc.58.1.69
Abstract
THE FIRST controlled clinical trial of bright light treatment for seasonal affective disorder (SAD)1 demonstrated a therapeutic effect with daily exposures in the morning and evening. Since then there have been numerous studies indicating an advantage of morning over evening light exposure in cross-center pooling of data2 and a Cochrane meta-analysis.3 Recently, 3 large clinical trials have further established a benefit over nonphotic placebo controls,4 the superiority of morning light over evening light exposure,5 or both.6Keywords
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