Influence of ferrous iron incorporation on the structure of hydroxyapatite
- 1 May 2005
- journal article
- Published by Springer Science and Business Media LLC in Journal of Materials Science: Materials in Medicine
- Vol. 16 (5), 387-392
- https://doi.org/10.1007/s10856-005-6976-5
Abstract
Iron is a vital element of cellular function within the body. High concentrations of iron can be found in the kidneys and the circulatory system. In bones and teeth it is present as a trace element. The use of iron-based compounds in combination with hydroxyapatite offers a new alternative for prosthetic devices. This work investigates the synthesis and processing of iron containing apatites as a possible new type of ceramic for biomedical devices. Stoichiometric and calcium deficient iron containing apatites were synthesized by a wet chemical reaction with di-ammonium-hydrogen-phosphate, calcium nitrate and a ferrous iron nitrate solution. A secondary phase of tri-calcium-phosphate (TCP) was observed after heat treatment of iron containing, calcium deficient, hydroxyapatite. The apatite structure was maintained after heat treatment of stoichiometric apatite, synthesized in the presence of iron. Sintering in air produced oxidation of Fe2+ to Fe3+, resulting in the formation of hematite as a secondary phase. The introduction of iron into the synthesis of hydroxyapatite causes: (i) an increase of the a-lattice parameter after synthesis and heat treatment in air; (ii) an increase in the c-lattice parameter after sintering in air.Keywords
This publication has 10 references indexed in Scilit:
- Mineralogical and Chemical Characterization of Iron‐, Manganese‐, and Copper‐Containing Synthetic HydroxyapatitesSoil Science Society of America Journal, 2003
- Fabrication of hydroxyapatite bodies by uniaxial pressing from a precipitated powderBiomaterials, 2001
- Distribution and chemical states of iron and chromium released from orthopedic implants into human tissuesX-Ray Spectrometry, 2001
- Processing and properties of hydroxyapatite-based biomaterials for use as hard tissue replacement implantsJournal of Materials Research, 1998
- Synthesis and characterisation of calcium deficient apatiteSolid State Ionics, 1997
- Infrared study of the formation, loss, and location of cyanate and cyanamide in thermally treated apatitesJournal of Solid State Chemistry, 1983
- Lattice defects in nonstoichiometric calcium hydroxylapatites. A chemical approachInorganic Chemistry, 1982
- Infrared absorption bands from NCO− and NCN2− in heated carbonate-containing apatites prepared in the presence of NH4 + IonsCalcified Tissue International, 1979
- Infrared studies of apatites. I. Vibrational assignments for calcium, strontium, and barium hydroxyapatites utilizing isotopic substitutionInorganic Chemistry, 1974
- Infra-red spectra of hydroxyapatite, octacalcium phosphate and pyrolysed octacalcium phosphateArchives of Oral Biology, 1966