Advances in engineering hydrogels
Top Cited Papers
- 5 May 2017
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 356 (6337)
- https://doi.org/10.1126/science.aaf3627
Abstract
Wet, soft, squishy, and tunable: Hydrogels are highly cross-linked polymer networks that are heavily swollen with water. Hydrogels have been used as dynamic, tunable, degradable materials for growing cells and tissues. Zhang and Khademhosseini review the advances in making hydrogels with improved mechanical strength and greater flexibility for use in a wide range of applications. Science , this issue p. eaaf3627Keywords
Funding Information
- National Institutes of Health (AR057837, DE021468, D005865, AR068258, AR066193, EB022403, EB021148)
- National Cancer Institute of the National Institutes of Health Pathway to Independence Award (K99CA201603)
This publication has 134 references indexed in Scilit:
- Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogelsNature Materials, 2013
- Bioorthogonal Click Chemistry: An Indispensable Tool to Create Multifaceted Cell Culture ScaffoldsACS Macro Letters, 2012
- Highly stretchable and tough hydrogelsNature, 2012
- Cytocompatible click-based hydrogels with dynamically tunable properties through orthogonal photoconjugation and photocleavage reactionsNature Chemistry, 2011
- Redox-responsive self-healing materials formed from host–guest polymersNature Communications, 2011
- Sequential assembly of cell‐laden hydrogel constructs to engineer vascular‐like microchannelsBiotechnology & Bioengineering, 2011
- Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fateNature Materials, 2010
- Surface‐directed assembly of cell‐laden microgelsBiotechnology & Bioengineering, 2009
- Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironmentsNature Materials, 2009
- Double‐Network Hydrogels with Extremely High Mechanical StrengthAdvanced Materials, 2003