Sharing of quorum-sensing signals and role of interspecies communities in a bacterial plant disease
- 16 June 2011
- journal article
- Published by Oxford University Press (OUP) in The ISME Journal
- Vol. 5 (12), 1857-1870
- https://doi.org/10.1038/ismej.2011.65
Abstract
Pathogenic bacteria interact not only with the host organism but most probably also with the resident microbial flora. In the knot disease of the olive tree (Olea europaea), the causative agent is the bacterium Pseudomonas savastanoi pv. savastanoi (Psv). Two bacterial species, namely Pantoea agglomerans and Erwinia toletana, which are not pathogenic and are olive plant epiphytes and endophytes, have been found very often to be associated with the olive knot. We identified the chemical signals that are produced by strains of the three species isolated from olive knot and found that they belong to the N-acyl-homoserine lactone family of QS signals. The luxI/R family genes responsible for the production and response to these signals in all three bacterial species have been identified and characterized. Genomic knockout mutagenesis and in planta experiments showed that virulence of Psv critically depends on QS; however, the lack of signal production can be complemented by wild-type E. toletana or P. agglomerans. It is also apparent that the disease caused by Psv is aggravated by the presence of the two other bacterial species. In this paper we discuss the potential role of QS in establishing a stable consortia leading to a poly-bacterial disease.Keywords
This publication has 57 references indexed in Scilit:
- Fate of aPseudomonas savastanoipv. savastanoi Type III Secretion System Mutant in Olive Plants (Olea europaeaL.)Applied and Environmental Microbiology, 2010
- Co-Swarming and Local Collapse: Quorum Sensing Conveys Resilience to Bacterial Communities by Localizing Cheater Mutants in Pseudomonas aeruginosaPLOS ONE, 2010
- Discerning the Complexity of Community Interactions Using a Drosophila Model of Polymicrobial InfectionsPLoS Pathogens, 2008
- Diffusible signals and interspecies communication in bacteriaMicrobiology, 2008
- The Acyl-Homoserine Lactone-Type Quorum-Sensing System Modulates Cell Motility and Virulence of Erwinia chrysanthemi pv. zeaeJournal of Bacteriology, 2008
- The Tomato Rhizosphere, an Environment Rich in Nitrogen-Fixing Burkholderia Species with Capabilities of Interest for Agriculture and BioremediationApplied and Environmental Microbiology, 2007
- Listening in on bacteria: acyl-homoserine lactone signallingNature Reviews Molecular Cell Biology, 2002
- Regulation of Gene Expression by Cell-to-Cell Communication: Acyl-Homoserine Lactone Quorum SensingAnnual Review of Genetics, 2001
- Four new derivatives of the broad-host-range cloning vector pBBR1MCS, carrying different antibiotic-resistance cassettesGene, 1995
- Studies on the role of indole-3-acetic acid and cytokinins in the formation of knots on olive and oleander plants by Pseudomonas syringae pv. savastanoiPhysiological Plant Pathology, 1985