Drugs as P-glycoprotein substrates, inhibitors, and inducers
Top Cited Papers
- 1 January 2002
- journal article
- review article
- Published by Taylor & Francis Ltd in Drug Metabolism Reviews
- Vol. 34 (1-2), 47-54
- https://doi.org/10.1081/dmr-120001389
Abstract
No abstract availableThis publication has 42 references indexed in Scilit:
- P-Glycoprotein, a gatekeeper in the blood–brain barrierAdvanced Drug Delivery Reviews, 1999
- BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTERAnnual Review of Pharmacology and Toxicology, 1999
- The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors.JCI Insight, 1998
- Identification of a P-Glycoprotein-Deficient Subpopulation in the CF-1 Mouse Strain Using a Restriction Fragment Length PolymorphismToxicology and Applied Pharmacology, 1997
- Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteinsProceedings of the National Academy of Sciences of the United States of America, 1997
- GENETIC ANALYSIS OF THE MULTIDRUG TRANSPORTERAnnual Review of Genetics, 1995
- Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugsCell, 1994
- Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver diseaseCell, 1993
- BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTERAnnual Review of Biochemistry, 1993
- Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.Proceedings of the National Academy of Sciences of the United States of America, 1987