Elastase Release from Human Alveolar Macrophages: Comparison Between Smokers and Nonsmokers
- 21 October 1977
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 198 (4314), 313-314
- https://doi.org/10.1126/science.910131
Abstract
Alveolar macrophages from smokers, in contrast to those of non-smokers, release elastase into serum-free culture medium. Since enzymes that digest elastin produce pulmonary emphysema in experimental animals, release of elastase by alveolar macrophages from smokers suggests that these cells are important in the pathogenesis of emphysema of smokers.This publication has 14 references indexed in Scilit:
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