Genetic studies of human diversity in East Asia
- 22 February 2007
- journal article
- Published by The Royal Society in Philosophical Transactions Of The Royal Society B-Biological Sciences
- Vol. 362 (1482), 987-996
- https://doi.org/10.1098/rstb.2007.2028
Abstract
East Asia is one of the most important regions for studying evolution and genetic diversity of human populations. Recognizing the relevance of characterizing the genetic diversity and structure of East Asian populations for understanding their genetic history and designing and interpreting genetic studies of human diseases, in recent years researchers in China have made substantial efforts to collect samples and generate data especially for markers on Y chromosomes and mtDNA. The hallmark of these efforts is the discovery and confirmation of consistent distinction between northern and southern East Asian populations at genetic markers across the genome. With the confirmation of an African origin for East Asian populations and the observation of a dominating impact of the gene flow entering East Asia from the south in early human settlement, interpretation of the north–south division in this context poses the challenge to the field. Other areas of interest that have been studied include the gene flow between East Asia and its neighbouring regions (i.e. Central Asia, the Sub-continent, America and the Pacific Islands), the origin of Sino-Tibetan populations and expansion of the Chinese.Keywords
This publication has 63 references indexed in Scilit:
- The Dazzling Array of Basal Branches in the mtDNA Macrohaplogroup M from India as Inferred from Complete GenomesMolecular Biology and Evolution, 2005
- Traces of Archaic Mitochondrial Lineages Persist in Austronesian-Speaking Formosan PopulationsPLoS Biology, 2005
- Phylogeny of Mitochondrial DNA Macrohaplogroup N in India, Based on Complete Sequencing: Implications for the Peopling of South AsiaAmerican Journal of Human Genetics, 2004
- POPULATION GENETICS, HISTORY, AND HEALTH PATTERNS IN NATIVE AMERICANSAnnual Review of Genomics and Human Genetics, 2004
- Y-chromosomal DNA haplogroups and their implications for the dual origins of the KoreansHuman Genetics, 2003
- The human Y chromosome: an evolutionary marker comes of ageNature Reviews Genetics, 2003
- The Genetic Heritage of the Earliest Settlers Persists Both in Indian Tribal and Caste PopulationsAmerican Journal of Human Genetics, 2003
- Three major lineages of Asian Y chromosomes: implications for the peopling of east and southeast AsiaHuman Genetics, 2001
- Sino-Tibetan Linguistics: Present State and Future ProspectsAnnual Review of Anthropology, 1991
- Mitochondrial DNA and human evolutionNature, 1987