Regulation of CYP3A4 and CYP2B6 expression by liver X receptor agonists
- 15 November 2007
- journal article
- Published by Elsevier BV in Biochemical Pharmacology
- Vol. 74 (10), 1535-1540
- https://doi.org/10.1016/j.bcp.2007.07.040
Abstract
No abstract availableKeywords
This publication has 22 references indexed in Scilit:
- T0901317 is a potent PXR ligand: Implications for the biology ascribed to LXRFEBS Letters, 2007
- Crystal structure of the PXR–T1317 complex provides a scaffold to examine the potential for receptor antagonismBioorganic & Medicinal Chemistry, 2007
- Pregnane X receptor (PXR) activation: A mechanism for neuroprotection in a mouse model of Niemann–Pick C diseaseProceedings of the National Academy of Sciences of the United States of America, 2006
- Differential Regulation of Hepatic CYP2B6 and CYP3A4 Genes by Constitutive Androstane Receptor but Not Pregnane X ReceptorThe Journal of pharmacology and experimental therapeutics, 2006
- LXR deficiency and cholesterol feeding affect the expression and phenobarbital-mediated induction of cytochromes P450 in mouse liverJournal of Lipid Research, 2005
- CYP3A INDUCTION BY LIVER X RECEPTOR LIGANDS IN PRIMARY CULTURED RAT AND MOUSE HEPATOCYTES IS MEDIATED BY THE PREGNANE X RECEPTORDrug Metabolism and Disposition, 2004
- Identification of a Novel Human Constitutive Androstane Receptor (CAR) Agonist and Its Use in the Identification of CAR Target GenesOnline Journal of Public Health Informatics, 2003
- Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearanceProceedings of the National Academy of Sciences of the United States of America, 2003
- Expression of CYP3A4, CYP2B6, andCYP2C9 Is Regulated by the Vitamin D Receptor Pathway in Primary Human HepatocytesOnline Journal of Public Health Informatics, 2002
- Pharmacophore Analysis of the Nuclear Oxysterol Receptor LXRαJournal of Medicinal Chemistry, 2001