Postimplantation development of blastomeres isolated from 4- and 8-cell mouse eggs
Open Access
- 1 October 1976
- journal article
- Published by The Company of Biologists in Development
- Vol. 36 (2), 283-290
- https://doi.org/10.1242/dev.36.2.283
Abstract
Blastomeres isolated from 4- and 8-cell mouse eggs were inserted into empty zonae and transferred to the oviduct. The products of both types of blastomere were capable of inducing decidual formation. One implant produced by an isolated blastomere from a 4-cell egg contained a small, retarded embryo at days but most decidua from blastomeres of either 4- or 8-cell eggs contained only a few trophoblast giant cells. It is suggested that this lack of totipotency is due to insufficient cells being present at cavitation rather than restriction in developmental potential.Keywords
This publication has 10 references indexed in Scilit:
- Haploid mouse blastocysts developed from bisected zygotesNature, 1976
- Does X Chromosome Inactivation Occur during Mitosis of First Cleavage?Nature, 1972
- TRANSFER TO THE MOUSE OVIDUCT OF EGGS WITH AND WITHOUT THE ZONA PELLUCIDAReproduction, 1970
- Storage of Two-Cell Mouse Embryos in VitroAustralian Journal of Biological Sciences, 1969
- DEVELOPMENTAL POTENTIAL OF SINGLE BLASTOMERES OF THE RABBIT EGGReproduction, 1968
- Studies of Regulation of Mouse Ova in vitroPublished by Wiley ,1965
- Experimental Study of the Developing Mammalian Egg: Removal of the Zona PellucidaScience, 1962
- TECHNIQUE OF PREPARATION, STUDY AND PHOTOGRAPHY OF BENZYL-BENZOATE CLEARED MATERIAL FOR EMBRYOLOGICAL STUDIESReproduction, 1962
- Experiments on the Development of Isolated Blastomeres of Mouse EggsNature, 1959
- Experimental studies on regulation in the development of isolated blastomeres of mouse eggsMammal Research, 1959