Association study of COX-2 (PTGS2) –765 G/C promoter polymorphism by pyrosequencing in Sicilian patients with Alzheimer’s disease

Abstract
Introduction : Alzheimer’s disease (AD) is characterized by progression of memory problems to a slow global decline of cognitive function. Inflammation when left unregulated becomes a major cofactor in the pathogenesis of AD. PTGS2 is of crucial relevance in the inflammatory response, and it...