A dual-emission and large Stokes shift fluorescence probe for real-time discrimination of ROS/RNS and imaging in live cells

Abstract
A novel dual-emission fluorescence probe has been developed for specific and sensitive detection of hypochlorite (ClO). Upon addition of ClO, significant changes in fluorescence emission intensity at two discrete wavelengths were observed. Meanwhile OONO led to only a single-channel fluorescence enhancement. This feature makes it a clear advantage in distinguishing ClO, RNS from other ROS.