Traditional usage, phytochemistry and pharmacology of Croton sylvaticus Hochst. ex C. Krauss
Open Access
- 1 May 2017
- journal article
- review article
- Published by Medknow in Asian Pacific Journal of Tropical Medicine
- Vol. 10 (5), 423-429
- https://doi.org/10.1016/j.apjtm.2017.05.002
Abstract
Croton sylvaticus (C. sylvaticus) is widely used as herbal medicine by the indigenous people of tropical Africa. The potential of C. sylvaticus as herbal medicine, the phytochemistry and pharmacological properties of its parts used as herbal medicines are reviewed. The extensive literature survey revealed that C. sylvaticus is traditionally used to treat or manage at least 24 human and animal diseases and ailments. The species is used as herbal medicine for diseases and ailments such as abdominal pains, boils, fever, inflammation, malaria, rheumatism, swellings and tuberculosis and as ethnoveterinary medicine. Multiple classes of phytochemicals such as alkaloids, anthraquinones, essential oils, flavonoids, lignan, phenolics, sterols, tannins and terpenoids have been isolated from the species. Scientific studies on C. sylvaticus indicate that it has a wide range of pharmacological activities which include antibacterial, antifungal, anti-inflammatory, antioxidant, larvicidal and effects on the central nervous system. Although studies have confirmed that C. sylvaticus has a wide range of bioactives, further research on the exact bioactive molecules and mechanisms of action are required.Keywords
This publication has 17 references indexed in Scilit:
- Ethnoknowledge of Bukusu community on livestock tick prevention and control in Bungoma district, western KenyaJournal of Ethnopharmacology, 2012
- Antifungal efficacy of ten selected South African plant species againstCryptococcus neoformansPharmaceutical Biology, 2010
- New diterpenoids from Croton sylvaticus and Croton pseudopulchellus (Euphorbiaceae) and antiplasmodial screening of ent-kaurenoic acidPlanta Medica, 2008
- Medicinal plants used in some gynaecological morbidity ailments in western UgandaAfrican Journal of Ecology, 2007
- Activity of traditional South African sedative and potentially CNS-acting plants in the GABA-benzodiazepine receptor assayJournal of Ethnopharmacology, 2005
- The suitability of Thin Layer Chromatography for authenticating bark medicines used in South African traditional healthcareSouth African Journal of Botany, 2003
- A lexicon of plants traded in the Witwatersrand umuthi shops, South AfricaBothalia, 2001
- Medicinal plants used in the promotion of animal health in TanzaniaRevue Scientifique et Technique de l'OIE, 1994
- A PRELIMINARY CHECK LIST OF ZULU NAMES OF PLANTSBantu Studies, 1941
- A PRELIMINARY CHECK LIST OF ZULU NAMES OF PLANTSBantu Studies, 1938