Cancer‐related fatigue and its impact on functioning
- 20 May 2013
- Vol. 119 (S11), 2124-2130
- https://doi.org/10.1002/cncr.28058
Abstract
This article presents the contrasting European and American perspectives on cancer‐related fatigue (CRF) and its impact on functioning in cancer survivors. The content is presented in 3 sections: state of the art, intervention studies, and future areas of research, followed by a discussion. Gaps identified include a lack of understanding of the etiology, definition, and measurement of CRF. Models to guide the study of CRF, selection of biomarkers, and design of interventions are needed. There is overlap between Europe and the United States concerning the future directions for research and collaboration related to CRF. The authors suggest the need for international consensus regarding the defining features of CRF in cancer survivors to identify phenotypes, a harmonized measurement of CRF outcomes using instruments that have demonstrated measurement equivalence across languages and cultures, and interventions (including exercise, rehabilitation, and psychoeducational) that have been manualized to permit intervention fidelity across diverse contexts. Coordinated intercontinental efforts would increase understanding of the biological, psychological, and social mechanisms underlying CRF and assist in the design of future intervention studies as well as revisions to clinical guidelines. Cancer 2013;119(11 suppl):2124‐30. © 2013 American Cancer Society.Keywords
This publication has 40 references indexed in Scilit:
- Exercise rehabilitation in patients with cancerNature Reviews Clinical Oncology, 2012
- Integrating cancer survivors' experiences into UK cancer registries: design and development of the ePOCS system (electronic Patient-reported Outcomes from Cancer Survivors)British Journal of Cancer, 2011
- Psychostimulants for the Management of Cancer-Related Fatigue: A Systematic Review and Meta-AnalysisJournal of Pain and Symptom Management, 2011
- Cancer-Related Fatigue and Rehabilitation: A Randomized Controlled Multicenter Trial Comparing Physical Training Combined With Cognitive-Behavioral Therapy With Physical Training Only and With No InterventionPTJ: Physical Therapy & Rehabilitation Journal, 2010
- ASCPRO Recommendations for the Assessment of Fatigue as an Outcome in Clinical TrialsJournal of Pain and Symptom Management, 2010
- Mind-Body Treatments for the Pain-Fatigue-Sleep Disturbance Symptom Cluster in Persons with CancerJournal of Pain and Symptom Management, 2010
- Physical activity interventions for cancer survivorsBritish Journal of Sports Medicine, 2008
- Systematic review and meta-analysis of psychological and activity-based interventions for cancer-related fatigue.Health Psychology, 2007
- Cancer-related fatigue: A critical appraisalEuropean Journal Of Cancer, 2006
- The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in OncologyJNCI Journal of the National Cancer Institute, 1993