Water Transport and Functional Dynamics of Aquaporins in Osmoregulatory Organs of Fishes
- 1 August 2015
- journal article
- review article
- Published by University of Chicago Press in The Biological Bulletin
- Vol. 229 (1), 70-92
- https://doi.org/10.1086/bblv229n1p70
Abstract
Aquaporins play distinct roles for water transport in fishes as they do in mammals—both at the cellular, organ, and organismal levels. However, with over 32,000 known species of fishes inhabiting almost every aquatic environment, from tidal pools, small mountain streams, to the oceans and extreme salty desert lakes, the challenge to obtain consensus as well as specific knowledge about aquaporin physiology in these vertebrate clades is overwhelming. Because the integumental surfaces of these animals are in intimate contact with the surrounding milieu, passive water loss and uptake represent two of the major osmoregulatory challenges that need compensation. However, neither obligatory nor regulatory water transport nor their mechanisms have been elucidated to the same degree as, for example, ion transport in fishes. Currently fewer than 60 papers address fish aquaporins. Most of these papers identify “what is present” and describe tissue expression patterns in various teleosts. The agnathans, chondrichthyans, and functionality of fish aquaporins generally have received little attention. This review emphasizes the functional physiology of aquaporins in fishes, focusing on transepithelial water transport in osmoregulatory organs in euryhaline species – primarily teleosts, but covering other taxonomic groups as well. Most current knowledge comes from teleosts, and there is a strong need for related information on older fish clades. Our survey aims to stimulate new, original research in this area and to bring together new collaborations across disciplines.Keywords
This publication has 98 references indexed in Scilit:
- Expression of aquaporin 3 in gills of the Atlantic killifish (Fundulus heteroclitus): Effects of seawater acclimationComparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 2012
- Osmoregulation and epithelial water transport: lessons from the intestine of marine teleost fishJournal of Comparative Physiology B, 2011
- Cloning and characterization of a zebrafish homologue of human AQP1: a bifunctional water and gas channelAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2010
- The zebrafish genome encodes the largest vertebrate repertoire of functional aquaporins with dual paralogy and substrate specificities similar to mammalsBMC Evolutionary Biology, 2010
- Water and Deuterium Oxide Permeability through Aquaporin 1: MD Predictions and Experimental VerificationThe Journal of general physiology, 2007
- Fast and Selective Ammonia Transport by Aquaporin-8Published by Elsevier BV ,2007
- Implications of the Aquaporin-4 Structure on Array Formation and Cell AdhesionJournal of Molecular Biology, 2006
- Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cellsBiochemical and Biophysical Research Communications, 2005
- From structure to disease: the evolving tale of aquaporin biologyNature Reviews Molecular Cell Biology, 2004
- Intestinal transport mechanisms and plasma cortisol levels during normal and out-of-season parr–smolt transformation of Atlantic salmon, Salmo salarAquaculture, 2003