A Computer Program for Aligning a cDNA Sequence with a Genomic DNA Sequence
Open Access
- 1 September 1998
- journal article
- Published by Cold Spring Harbor Laboratory in Genome Research
- Vol. 8 (9), 967-974
- https://doi.org/10.1101/gr.8.9.967
Abstract
We address the problem of efficiently aligning a transcribed and spliced DNA sequence with a genomic sequence containing that gene, allowing for introns in the genomic sequence and a relatively small number of sequencing errors. A freely available computer program, described herein, solves the problem for a 100-kb genomic sequence in a few seconds on a workstation.Keywords
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