Endometrial micropolyps at fluid hysteroscopy suggest the existence of chronic endometritis
Open Access
- 1 May 2005
- journal article
- Published by Oxford University Press (OUP) in Human Reproduction
- Vol. 20 (5), 1386-1389
- https://doi.org/10.1093/humrep/deh779
Abstract
BACKGROUND: At fluid hysteroscopy the presence of endometrial micropolyps (less than 1 mm of size) is a frequent finding. Although their origin is still unknown, in our experience they are associated with stromal edema, endometrial thickening and periglandular hyperhaemia that suggest the existence of chronic endometritis. This study will aim to describe these lesions and evaluate their inflammatory significance by comparing hysteroscopic and histological findings. METHODS: 820 women underwent hysteroscopy and endometrial biopsy. Sensitivity, specificity, positive and negative predictive values and accuracy of the micropolyps presence for the diagnosis of chronic endometritis were calculated. RESULTS: Micropolyps were found in 96 cases (11.7% of all hysteroscopies); in 90 (93.7%) of these cases histology confirmed the presence of chronic endometritis. In women without micropolyps, chronic endometritis was significantly less frequent (78 cases, 10.8%) (P<0.000001). The likelihood of chronic endometritis for women with micropolyps was very high (odds ratio 124.2, confidence interval 50.3–205.4). The sensitivity, specificity, positive and negative predictive values were 54%, 99%, 94% and 89%, respectively; the diagnostic accuracy was 90%. CONCLUSIONS: The presence of endometrial micropolyps at fluid hysteroscopy is significantly associated with endometrial inflammation and can be considered a reliable diagnostic sign for this pathology.Keywords
This publication has 8 references indexed in Scilit:
- Reliability, feasibility, and safety of minihysteroscopy with a vaginoscopic approach: experience with 6,000 casesFertility and Sterility, 2003
- Classification of Microhysteroscopic Images and their Correlation with Histologic DiagnosesThe Journal of the American Association of Gynecologic Laparoscopists, 2003
- Vaginal polymorphonuclear leukocytes and bacterial vaginosis as markers for histologic endometritis among women without symptoms of pelvic inflammatory diseaseAmerican Journal of Obstetrics and Gynecology, 2003
- Investigation of the infertile couple : A one-stop outpatient endoscopy-based approachHuman Reproduction, 2002
- Instrumentation and distention media for the hysteroscopic treatment of abnormal uterine bleeding.Obstetrics and Gynecology Clinics of North America, 2000
- The association of interleukin 6 with clinical and laboratory parameters of acute pelvic inflammatory diseaseAmerican Journal of Obstetrics and Gynecology, 1999
- Evaluation of Endometrial Inflammation by Quantification of Macrophages, T Lymphocytes, and Interleukin-1 and -6 in Human EndometriumJournal of Assisted Reproduction and Genetics, 1998
- Eenie, meenie, minie, mo … What do the data really show?American Journal of Obstetrics and Gynecology, 1982