A Titanium-Catalyzed Three-Component Coupling To Generate α,β-Unsaturated β-Iminoamines
- 12 February 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 125 (10), 2880-2881
- https://doi.org/10.1021/ja0284714
Abstract
The three-component coupling of an amine, alkyne, and isonitrile is facilitated by a titanium complex bearing the N,N-di(pyrrolyl-α-methyl)-N-methylamine (dpma) ligand. From this methodology, α,β-unsaturated β-iminoamines are generated regioselectively with many substrates and are available on multigram scales.Keywords
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