TESTICULAR DAMAGE AFTER RADIOACTIVE IODINE (I‐131) THERAPY FOR THYROID CANCER
- 1 May 1983
- journal article
- Published by Wiley in Clinical Endocrinology
- Vol. 18 (5), 465-472
- https://doi.org/10.1111/j.1365-2265.1983.tb02876.x
Abstract
Testicular damage was evaluated in twelve men by determination of sperm counts, serum FSH, LH, and testosterone up to 3 1/2 years after treatment with radioactive iodine (131I) therapy for thyroid cancer. Dose-dependent spermatogenic damage with elevation of serum FSH was evident. Full recovery in one and partial recovery in another patient was documented during 2 1/2 years of follow-up. Serial study in two patients documented a small but significant effect of 50 mCi 131I on serum FSH levels and clinically important effects appear to be restricted to men having multiple doses totalling over 100 mCi.Keywords
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