Long-term leucine supplementation does not increase muscle mass or strength in healthy elderly men
- 1 May 2009
- journal article
- research article
- Published by Elsevier BV in The American Journal of Clinical Nutrition
- Vol. 89 (5), 1468-1475
- https://doi.org/10.3945/ajcn.2008.26668
Abstract
Background: It has been reported that the blunted muscle protein synthetic response to food intake in the elderly can be normalized by increasing the leucine content of a meal.Keywords
This publication has 33 references indexed in Scilit:
- Increasing Dietary Leucine Intake Reduces Diet-Induced Obesity and Improves Glucose and Cholesterol Metabolism in Mice via MultimechanismsDiabetes, 2007
- Satellite cell content is specifically reduced in type II skeletal muscle fibers in the elderlyAmerican Journal of Physiology-Endocrinology and Metabolism, 2007
- Protein Hydrolysate/Leucine Co-Ingestion Reduces the Prevalence of Hyperglycemia in Type 2 Diabetic PatientsDiabetes Care, 2006
- Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemiaThe Journal of Physiology, 2006
- A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderlyAmerican Journal of Physiology-Endocrinology and Metabolism, 2006
- Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey proteinExperimental Gerontology, 2006
- Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscleThe FASEB Journal, 2004
- Age and aerobic exercise training effects on whole body and muscle protein metabolismAmerican Journal of Physiology-Endocrinology and Metabolism, 2004
- Timing of postexercise protein intake is important for muscle hypertrophy with resistance training in elderly humansThe Journal of Physiology, 2001
- What Is Sarcopenia?The Journals of Gerontology: Series A, 1995