Supplementary Data from PWD/Ph-Encoded Genetic Variants Modulate the Cellular Wnt/β-Catenin Response to Suppress ApcMin-Triggered Intestinal Tumor Formation
Supplementary Figures 1-7. Supplementary Figure 1: Assembly of the PWD genome and alignment to the C57BL/6 genome. Supplementary Figure 2: RNA-seq read assignment. Supplementary Figure 3: MeDIP-seq quality controls. Supplementary Figure 4: Histology and distribution of tumors in B6 x PWD consomic mice. Supplementary Figure 5: Transcriptome analyses identify modifier candidate genes on other chromosomes than chromosome 5. Supplementary Figure 6: Strain-specific DNA methylation on chromosome 5 is correlated to CpG availability. Supplementary Figure 7: Assessment of cell types in the intestinal crypt.