Active Transcriptional Repression by the Rb–E2F Complex Mediates G1 Arrest Triggered by p16INK4a, TGFβ, and Contact Inhibition
Open Access
- 2 April 1999
- journal article
- Published by Elsevier BV in Cell
- Vol. 97 (1), 53-61
- https://doi.org/10.1016/s0092-8674(00)80714-x
Abstract
No abstract availableKeywords
This publication has 62 references indexed in Scilit:
- Cancer Cell CyclesScience, 1996
- E2F and Cell Proliferation: A World Turned Upside DownCell, 1996
- E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity.Genes & Development, 1995
- Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpointCell, 1995
- Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibitionNature, 1995
- Binding to DNA and the Retinoblastoma Gene Product Promoted by Complex Formation of Different E2F Family MembersScience, 1993
- A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4Nature, 1993
- Negative Regulation of G1 in Mammalian Cells: Inhibition of Cyclin E-Dependent Kinase by TGF-βScience, 1993
- Retinoblastoma protein switches the E2F site from positive to negative elementNature, 1992
- The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large TCell, 1990