Novel electrode technologies for neural recordings
Top Cited Papers
- 4 March 2019
- journal article
- review article
- Published by Springer Science and Business Media LLC in Nature Reviews Neuroscience
- Vol. 20 (6), 330-345
- https://doi.org/10.1038/s41583-019-0140-6
Abstract
Neural recording electrode technologies have contributed considerably to neuroscience by enabling the extracellular detection of low-frequency local field potential oscillations and high-frequency action potentials of single units. Nevertheless, several long-standing limitations exist, including low multiplexity, deleterious chronic immune responses and long-term recording instability. Driven by initiatives encouraging the generation of novel neurotechnologies and the maturation of technologies to fabricate high-density electronics, novel electrode technologies are emerging. Here, we provide an overview of recently developed neural recording electrode technologies with high spatial integration, long-term stability and multiple functionalities. We describe how these emergent neurotechnologies can approach the ultimate goal of illuminating chronic brain activity with minimal disruption of the neural environment, thereby providing unprecedented opportunities for neuroscience research in the future.Keywords
This publication has 157 references indexed in Scilit:
- Recent advances in optogenetics and pharmacogeneticsBrain Research, 2013
- In vivo recordings of brain activity using organic transistorsNature Communications, 2013
- Macroporous nanowire nanoelectronic scaffolds for synthetic tissuesNature Materials, 2012
- Synthetically Encoded Ultrashort-Channel Nanowire Transistors for Fast, Pointlike Cellular Signal DetectionNano Letters, 2012
- Neuronal basis of age-related working memory declineNature, 2011
- Chronic in vivo multi-circuit neurophysiological recordings in miceJournal of Neuroscience Methods, 2011
- How advances in neural recording affect data analysisNature Neuroscience, 2011
- Regulation of synaptic connectivity by gliaNature, 2010
- Microstructure of a spatial map in the entorhinal cortexNature, 2005
- The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving ratBrain Research, 1971