Risk Factors for Laryngeal Cancer in Montenegro
- 1 January 2008
- journal article
- research article
- Published by Walter de Gruyter GmbH in Archives of Industrial Hygiene and Toxicology
- Vol. 59 (1), 11-18
- https://doi.org/10.2478/10004-1254-59-2008-1863
Abstract
Laryngeal cancer is the most common head and neck cancer. There might be many risk factors for laryngeal cancer. Smoking, especially cigarette smoking and alcohol are indisputable risk factors. The authors of this paper assessed the presumed risk factors in order to identify possible aetiological agents of the disease. A hospital-based case-control study was conducted. The study group consisted of 108 histologically verified laryngeal cancer patients and 108 hospital controls matched by sex, age ( 3 years) and place of residence. Laryngeal cancer patients and controls were interviewed during their hospital stay using a structured questionnaire. According to multiple logistic regression analysis six variables were independently related to laryngeal cancer: hard liquor consumption (Odd Ratio /OR/ = 2.93, Confidence Interval /CI/ 95 % = 1.17 to 7.31), consumption more than 2 alcoholic drinks per day (OR= 4.96, CI 95 % = 2.04 to 12.04), cigarette smoking for more than 40 years (OR= 4.32, CI 95 % = 1.69 to 11.06), smoking more than 30 cigarettes per day (OR=4.24, CI 95 % = 1.75 to 10.27), coffee consumption more than 5 cups per day (OR=4.52, Cl 95 % = 1.01 to 20.12) and carbonated beverage consumption (OR=0.38, CI 95 %= 0.16 to 0.92). The great majority of laryngeal cancers could be prevented by eliminating tobacco smoking and alcohol consumption.Keywords
This publication has 36 references indexed in Scilit:
- Alcohol, smoking and human papillomavirus in laryngeal carcinoma: a Nordic prospective multicenter studyZeitschrift für Krebsforschung und Klinische Onkologie, 2007
- Non-alcoholic beverages and risk of bladder cancer in UruguayBMC Cancer, 2007
- Coffee consumption and stomach cancer risk in a cohort of Swedish womenInternational Journal of Cancer, 2006
- Cyclin D1 A870G polymorphism and amplification in laryngeal squamous cell carcinoma: implications of tumor localization and tobacco exposureCancer Detection Prevention, 2004
- Risk of Laryngeal Cancer by Occupational Chemical Exposure in TurkeyJournal of Occupational and Environmental Medicine, 2003
- Risk factors for oesophageal, lung, oral and laryngeal cancers in black South AfricansBritish Journal of Cancer, 2002
- Alcohol's Effect on the Development and Progression of CancerNutrition in Clinical Care, 2000
- Global cancer statisticsCA: A Cancer Journal for Clinicians, 1999
- Risk factors for laryngeal cancerEuropean Journal of Epidemiology, 1995
- Carcinogenesis of laryngeal carcinomaThe Laryngoscope, 1975