Sphingosine Kinase 1 Is Associated with Gastric Cancer Progression and Poor Survival of Patients
Open Access
- 15 February 2009
- journal article
- Published by American Association for Cancer Research (AACR) in Clinical Cancer Research
- Vol. 15 (4), 1393-1399
- https://doi.org/10.1158/1078-0432.ccr-08-1158
Abstract
Purpose: The present study was to investigate the clinical significance of sphingosine kinase 1 (SPHK1), an oncoenzyme, in the development and progression of gastric cancer.Keywords
Other Versions
This publication has 36 references indexed in Scilit:
- Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancerBreast Cancer Research and Treatment, 2007
- Advances in the treatment of patients with gastric adenocarcinomaActa Oncologica, 2007
- Intracellular Role for Sphingosine Kinase 1 in Intestinal Adenoma Cell ProliferationMolecular and Cellular Biology, 2006
- Antitumor Activity of Sphingosine Kinase InhibitorsJournal of Pharmacology and Experimental Therapeutics, 2006
- High expression of sphingosine kinase 1 and S1P receptors in chemotherapy-resistant prostate cancer PC3 cells and their camptothecin-induced up-regulationBiochemical and Biophysical Research Communications, 2006
- Sphingosine Kinase-1 as a Chemotherapy Sensor in Prostate Adenocarcinoma Cell and Mouse ModelsCancer Research, 2005
- Sphingosine Kinase Protects Lipopolysaccharide-Activated Macrophages from ApoptosisMolecular and Cellular Biology, 2004
- Generation and metabolism of bioactive sphingosine‐1‐phosphateJournal of Cellular Biochemistry, 2004
- Sphingosine-1-phosphate: an enigmatic signalling lipidNature Reviews Molecular Cell Biology, 2003
- Cancer Statistics, 2002CA: A Cancer Journal for Clinicians, 2002