Formamidine as a Versatile Protecting Group for Primary Amines: A Mild Procedure for Hydrolytic Removal
- 1 June 1994
- journal article
- research article
- Published by Taylor & Francis Ltd in Synthetic Communications
- Vol. 24 (11), 1617-1624
- https://doi.org/10.1080/00397919408010163
Abstract
A mild, zinc chloride-promoted cleavage of N,N-dimethyl-formamidine derivatives of primary amines to the free amines is described. Under slightly different hydrolytic conditions the corresponding N-formyl derivatives can be isolated.Keywords
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