Target identification of natural products and bioactive compounds using affinity-based probes
- 18 November 2015
- journal article
- review article
- Published by Royal Society of Chemistry (RSC) in Natural Product Reports
- Vol. 33 (5), 612-620
- https://doi.org/10.1039/c5np00101c
Abstract
Direct capture of drug–target complexesin situby using affinity-based probes allows target identification of natural products and bioactive compounds, even if the binding is reversible with moderate affinity.Keywords
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